Friday, June 20, 2025

What challenges do gig workers face?

 What challenges do gig workers face?

Gig workers face several challenges, primarily revolving around the nature of temporary, project-based work and the associated lack of traditional employment benefits.




Here are the key challenges:

•Lack of assured income and job security: Gig jobs are temporary and project-based, meaning workers do not have a guaranteed steady income. This makes their financial situation less predictable than that of full-time employees.

•Absence of social security benefits: Gig workers typically lack social security benefits such as Provident Fund (PF), Employee State Insurance (ESI), or health insurance, which are common for full-time employees. Recognizing this as a significant challenge, the Government of India has announced initiatives to provide gig workers with identity cards, e-Shram registration, and healthcare security under PM Jan Arogya Yojana. Additionally, the Karnataka government has established a Platform-Based Gig Workers Welfare Board to provide social security and welfare benefits.

•Risk regarding client credibility: There is a risk concerning the credibility of clients on gig platforms.

•Possibility of delayed payments: Gig professionals may face the possibility of delayed payments from platforms.

•Self-management of career growth and upskilling: A gig professional's income growth is entirely dependent on their own efforts in self-upskilling to align with in-demand skills. They are solely responsible for managing their career progression.

What are the necessary ecosystem changes to sustain and scale new collar gig work?

 What are the necessary ecosystem changes to sustain and scale new collar gig work?

To sustain and scale new collar gig work, the sources indicate that all concerned stakeholders—Higher Educational Institutions (HEIs), industry, and government—need to play an active role in addressing challenges and making the gig economy sustainable, scalable, and viable.

Here are the necessary ecosystem changes:

Role of Higher Educational Institutions (HEIs):

◦Prepare students for gig roles by including modules on freelancing, digital marketing, and financial literacy as part of the curriculum.

◦Impart contemporary skills and conduct credit-based evaluation of gig projects.

◦Collaborate with the industry to provide gig platforms and startups for short live project opportunities.

◦Encourage students to showcase their skills through live projects using platforms like GitHub, Dribbble, and Kaggle.

◦Set up mentoring and counseling support for students and recognize top-performers.

◦Examples of such initiatives include BITS Pilani introducing a "Freelancing" module and IIT Madras partnering with Zoho for gig internships.


Role of the Industry:

◦Create dedicated gig platforms for engineers.

◦Offer micro-internships and gig projects to students.

◦Maintain pools of vetted freelancers for just-in-time hiring.

◦Create talent pipelines, offering regular employment to well-performing gig professionals.

◦Provide upskilling opportunities for enrolled gig workers.


◦Examples include TCS curating the Ion Digital Marketplace, which has onboarded over 15,000 gig workers and absorbed about 40% of top performers into projects, and Wells Fargo establishing a "Gig Talent Pool" to hire Indian freelancers for fraud analytics and AI jobs.

Role of the Government:

◦Recognize the gig workforce as a vital pillar of the new-age economy.

◦Provide social security and well-being initiatives for gig workers, such as identity cards, e-Shram registration, and healthcare security under PM Jan Arogya Yojana. This initiative is expected to empower nearly 10 million gig workers.

◦Undertake pilot initiatives to register platform workers and aggregators, as the Ministry of Labour & Employment has done with the e-Shram portal.

◦Establish Platform-Based Gig Workers Welfare Boards to provide social security and welfare benefits, as the Karnataka government has done, with other states expected to follow.

◦Consider setting up a "Gig India Mission" and formulating strategies and action plans to realize India's potential as a Global Gig Hub for new-collar skills.


These concerted efforts are crucial for the gig careers to evolve from short-term sustenance models to long-term rewarding professional careers, offering opportunities for higher income, growth, and innovation. This approach can help India leverage its demographic dividend for achieving the goal of Viksit Bharat 2047 by rightly skilling its youth.

Thursday, June 19, 2025

What are the necessary ecosystem changes to sustain and scale new collar gig work?

What are the necessary ecosystem changes to sustain and scale new collar gig work?

To sustain and scale new collar gig work, the sources indicate that all concerned stakeholders—Higher Educational Institutions (HEIs), industry, and government—need to play an active role in addressing challenges and making the gig economy sustainable, scalable, and viable.

Here are the necessary ecosystem changes:

•Role of Higher Educational Institutions (HEIs):

◦Prepare students for gig roles by including modules on freelancing, digital marketing, and financial literacy as part of the curriculum.

◦Impart contemporary skills and conduct credit-based evaluation of gig projects.

◦Collaborate with the industry to provide gig platforms and startups for short live project opportunities.

◦Encourage students to showcase their skills through live projects using platforms like GitHub, Dribbble, and Kaggle.

◦Set up mentoring and counseling support for students and recognize top-performers.

◦Examples of such initiatives include BITS Pilani introducing a "Freelancing" module and IIT Madras partnering with Zoho for gig internships.

•Role of the Industry:

◦Create dedicated gig platforms for engineers.

◦Offer micro-internships and gig projects to students.

◦Maintain pools of vetted freelancers for just-in-time hiring.

◦Create talent pipelines, offering regular employment to well-performing gig professionals.

◦Provide upskilling opportunities for enrolled gig workers.

◦Examples include TCS curating the Ion Digital Marketplace, which has onboarded over 15,000 gig workers and absorbed about 40% of top performers into projects, and Wells Fargo establishing a "Gig Talent Pool" to hire Indian freelancers for fraud analytics and AI jobs.

•Role of the Government:

◦Recognize the gig workforce as a vital pillar of the new-age economy.

◦Provide social security and well-being initiatives for gig workers, such as identity cards, e-Shram registration, and healthcare security under PM Jan Arogya Yojana. This initiative is expected to empower nearly 10 million gig workers.

◦Undertake pilot initiatives to register platform workers and aggregators, as the Ministry of Labour & Employment has done with the e-Shram portal.

◦Establish Platform-Based Gig Workers Welfare Boards to provide social security and welfare benefits, as the Karnataka government has done, with other states expected to follow.

◦Consider setting up a "Gig India Mission" and formulating strategies and action plans to realize India's potential as a Global Gig Hub for new-collar skills.

These concerted efforts are crucial for the gig careers to evolve from short-term sustenance models to long-term rewarding professional careers, offering opportunities for higher income, growth, and innovation. This approach can help India leverage its demographic dividend for achieving the goal of Viksit Bharat 2047 by rightly skilling its youth.

 


Maternal domestic violence linked with depressive disorders in adolescents, Indian study finds

 Maternal domestic violence linked with depressive disorders in adolescents, Indian study finds

The study highlights a critical public health concern: exposure to maternal abuse poses a direct and longterm risk to adolescent mental health, highlighting the urgent need for trauma-informed prevention and intervention strategies

Domestic violence is abuse within a household, involving not just partners but also other family members. Often driven by gendered power dynamics, it disproportionately affects mothers and exposes children to direct harm and related health risks |Image used for representational purpose only

Domestic violence is abuse within a household, involving not just partners but also other family members. Often driven by gendered power dynamics, it disproportionately affects mothers and exposes children to direct harm and related health risks |Image used for representational purpose only |

A new multi-site study from India has revealed troubling associations between maternal experiences of domestic violence (DV) and adolescent mental health outcomes. Conducted across seven urban and rural locations, this large-scale analysis is the first of its kind in the Indian context to show significant links between maternal abuse -- psychological, physical or sexual -- and increased rates of anxiety and depression among adolescents.

The study analysed responses from 2,784 adolescent-mother pairs, focusing on the connections between maternal DV and adolescent mental disorders such as anxiety and depression. The results suggest that maternal exposure to DV particularly physical abuse is significantly associated with higher rates of mental health disorders in children, even after adjusting for factors such as site, gender and education status.

The study published in the journal PLOS One, draws on secondary analysis of data from the Consortium on Vulnerability to Externalising Disorders and Addictions (cVEDA). Data collection was carried out through private face-to-face interviews conducted by trained research staff, including psychologists and health professionals certified in nursing or related fields. Each mother-child pair was interviewed at their respective study site in a confidential setting.

During this process, adolescents were directly administered the Standard of Living Index–Modified (SDI-M), Wealth Index, and MINI-Kid, all in the presence of their mothers. In contrast, the Domestic Violence questionnaire -- based on the Indian Family Violence and Control Scale (IFVCS) was administered privately to mothers. The Adverse Childhood Experiences–International Questionnaire (ACE-IQ) was administered directly and privately to the adolescent participants. All instruments were translated into the appropriate regional languages and administered in the participant’s primary language .

 Health risks and cultural implications of maternal violence

The most significant association identified was between maternal physical abuse and adolescent depressive disorders, suggesting that trauma in the household has ripple effects on children. According to the study’s principal investigator, Amritha Gourisankar, resident physician, Internal Medicine-Paediatrics , University of Minnesota, this may reflect the longer duration or severity of abuse. “There is evidence to show that physical abuse is a later manifestation of domestic violence -- those experiencing physical abuse have often experienced psychological abuse before as well,” she noted. “The presence of physical abuse may suggest a progression or length of time of the abuse that may drive the association with adolescent depressive disorders.”

The findings also highlight the importance of recognising non-visible forms of violence. Psychological abuse, often harder to detect, was still significantly linked to anxiety and depression among adolescents. “These experiences in homes are being observed and absorbed by children,” Dr. Gourisankar said. “Knowing the prevalence of domestic violence and its impact can lead to earlier conversations with children, improved screening in schools, and more informal supports in communities.”

Unlike standard Western surveys, the IFVCS included context-specific references such as dowry-related threats and restrictions on visiting one’s natal home, making the experience of abuse more recognisable and reportable. “By asking the questions in a culturally relevant way, we’re able to get more accurate responses,” Dr. Gourisankar explained. “People may recognise the violence they’re experiencing that they otherwise might not have.”

. “In our region, domestic violence often involves extended family members-- not just the husband. In many cases, the in-laws join in the abuse, leaving women with no refuge -- neither in their marital homes nor at their natal homes, where returning is seen as taboo,” said R.K. Lenin Singh, professor and former head, department of psychiatry, Regional Institute of Medical Sciences, Imphal, Manipur, and co-author of the study. The resulting trauma for women is often silently endured, but its effects are not: “Adolescents, who begin to understand the household dynamics, are caught in this pain, confused and helpless, unable to intervene or escape,” he added.

In such contexts, the mental health burden is compounded by social and familial expectations, including stigma around leaving a marriage, the absence of a male child, or infertility -- all of which can exacerbate domestic tensions. “These are not common drivers of domestic violence in many Western countries,” Dr. Singh noted, “but they are crucial to understand in our settings if we are to develop meaningful mental health interventions.”

 The impact of violence on a child’s mind

Call for trauma- informed systems rooted in empathy

The implications of this research go beyond epidemiological significance -- they call for trauma-informed interventions in schools, communities, and healthcare systems. Dr. Gourisankar emphasises the critical role of frontline workers such as ASHA workers, teachers, and paediatricians. “Healthcare systems -- particularly those embedded in communities -- need more support in recognising trauma symptoms in children,” she said. “This includes changes in mood and behaviour, withdrawal or aggression. Trainings led by psychologists can empower community-level workers to act as early responders.”

Dr. Singh reinforced this point: “In our communities, ASHA workers know the ground realities. They see what doctors and teachers often don’t -- because it’s taboo to talk about abuse, especially within families. If equipped with the right tools, ASHAs could play a transformative role in recognising and addressing mental health concerns in adolescents stemming from domestic violence,” he said.

While national programmes on school mental health exist, Dr. Singh expressed concern about the gap in implementation in many northeastern states. “Most schools in Manipur don’t have even a part-time counsellor. Yet, we are seeing increasing rates of mental health issues in students, from anxiety and exam stress to ADHD. Without basic screening and support systems in place, these children are left to cope alone.”

Interestingly, while the study accounted for household structure (joint vs. nuclear families), this variable did not significantly affect the associations between maternal DV and adolescent mental health. Still, the researchers argued that future qualitative investigations into in-law dynamics may offer deeper insights into how extended family structures shape domestic violence experiences.

 Sexual assault survivors need trauma-informed mental health interventions, say experts

Study limitations and the need for further research

The genesis of this work lies in the cVEDA project, a large-scale research initiative focused on the role of environment -- including genetics, pollution, and domestic violence -- on the mental health of children and adolescents. “Our site at RIMS in Imphal was part of one of the largest adolescent mental health cohorts in India,” Dr. Singh said. “Although funding gaps briefly stalled the project, we are now continuing under a modified initiative, PARAM. More than 30 papers have been published across journals from this data, exploring everything from genetic vulnerabilities to the role of parental substance abuse.”

The study however, is not without limitations. One key concern is the potential for participant fatigue, given the length of the four-hour survey battery, which may have affected response reliability.


Also, the study was unable to control for all potential confounders known to influence adolescent mental health, such as family history of mental illness or parental substance use, due to the limitations of the parent dataset. Future research using longitudinal designs, qualitative approaches and focused exploration of intergenerational trauma, in-law dynamics and cultural stigmas can offer a more nuanced understanding of how domestic violence shapes adolescent mental health in Indian contexts.

“Understanding how domestic violence is experienced in India, and how it affects the mental health of adolescents, allows us to design better tools, support systems, and prevention strategies,” Dr. Gourisankar said. In a country where one in three women experience domestic violence, and youth mental health challenges are rising, this research urges families, schools, and systems to listen more carefully -- and respond more holistically --to the children caught in the silence of abuse.


Why regular kidney cancer screening after 40 is a must

 Why regular kidney cancer screening after 40 is a must 

 

Screening after the age of 40—especially for high-risk individuals—can help detect tumours while they are still small, localised, and curable

 

Globally, over 4,00,000 people are diagnosed with kidney cancer each year, and the numbers are steadily rising. Photograph used for representational purposes only

Globally, over 4,00,000people are diagnosed with kidney cancer each year, and the numbers are steadily rising. Photograph used for representational purposes only | 

 

Kidney cancer, often dubbed a “silent killer,” is one of the most underdiagnosed cancers globally. It is frequently discovered incidentally during imaging for unrelated conditions, especially if detected at an early stage. With World Kidney Cancer Day being observed on June 19, the 2025 campaign theme, ‘Show Your Kidneys Some Love,’ is a timely reminder to prioritise kidney health—particularly through early screening and timely intervention, especially for individuals aged 40 and above.

 

The growing burden of kidney cancer

Globally, over 4,00,000people are diagnosed with kidney cancer each year, and the numbers are steadily rising. In India, the incidence has nearly doubled over the past two decades. Risk factors include smoking, obesity, hypertension, chronic kidney disease, and a family history of renal cancer. With these risk factors becoming increasingly prevalent, early detection through regular screening becomes not just important—but life-saving.

 

Most kidney cancers are diagnosed in individuals between the ages of 50 and 70, but cellular changes begin much earlier. By the age of 40, many individuals begin to experience the cumulative effects of risk factors such as lifestyle-related disorders. Unfortunately, kidney cancer often remains asymptomatic in its early stages. Symptoms such as blood in the urine, unexplained weight loss, persistent pain in the back or side, or fatigue typically appear only in the more advanced stages.

 

Screening after the age of 40—especially for high-risk individuals—can help detect tumours while they are still small, localised, and curable. Imaging techniques like ultrasound, CT scans, and urine cytology can be powerful tools when used proactively.

 

 Changing the narrative through prevention

Preventive healthcare is still evolving in India, and cancer screening is often reactive rather than proactive. Awareness needs to be raised about the fact that just like mammograms or colonoscopies kidney cancer screening should become routine, especially for those with a family history or those with chronic conditions like hypertension and diabetes.

 

Furthermore, India lacks a national screening programme for kidney cancer. Hospitals and healthcare providers must take the lead in encouraging annual kidney health evaluations, which can include a simple ultrasound and urine test.

 

The role of hospitals and specialists

The need for preventive uro-oncology must be emphasised by hospitals and specialists. There is firsthand experience to show that early diagnosis not only saves lives but also preserves kidney function, improves quality of life, and reduces the burden of treatment.

 

Newer, minimally invasive surgical options and targeted therapies have dramatically improved outcomes, but their success hinges on early-stage detection. Our message to all adults above 40—particularly those with risk factors—is clear: Do not wait for symptoms. Screen early. Screen regularly.

 

Advancing equitable access to kidney care

 

As we mark World Kidney Cancer Day let us commit to moving from awareness to action. Screening for kidney cancer after 40 isn’t just advisable—it is essential. Do not wait for symptoms. Love your kidneys enough to get them checked.

India's Science Brain Drain and Challenges in Attracting International Scientists

 


India's Science Brain Drain and Challenges in Attracting International Scientists

 India's Science Brain Drain and Challenges in Attracting International Scientists

 Nobel Laureate Venki Ramakrishnan regarding India's challenges in attracting international scientists, particularly in light of recent funding cuts in the U.S. The analysis highlights issues related to funding, infrastructure, policy, and the general socio-environmental landscape in India, contrasting it with more attractive scientific destinations.

Main Themes and Key Ideas:

1. Limited Attractiveness of India for International Scientists:

"India does not offer any of these advantages." Ramakrishnan unequivocally states that India lacks the crucial incentives that attract top-tier international scientists.

"I do not see India as a general magnet for international science." Despite having a few reputable institutions (IISc, NCBS, TIFR, IISERs, IITs), these are "world class only in some very specific areas," making India unattractive as a broad scientific destination.

Comparison to Europe: Given a choice between European countries and India, Ramakrishnan "strongly vouches Europe as 'far more attractive as a scientific destination'."

2. Inadequate Funding for R&D:

Insufficient GDP Allocation: "India’s R&D investment as a fraction of GDP is much less than China’s and is about a third or less of what many developed countries have, and far below countries like South Korea. It will not be competitive without a substantial increase." While funding has increased in absolute terms, its percentage of GDP has actually decreased.

Lack of Long-Term Assured Funding: Basic research, crucial for attracting U.S. researchers, lacks guaranteed long-term funding in India.

Dominance of Public Funding & Negligible Private Investment: "In India, it [private to public investment ratio] is almost the opposite. This is really a failing on the part of Indian industry." The government's ambitious ANRF initiative (₹50,000 crore) has secured only ₹14,000 crore in budgetary provision, with the vast majority dependent on "donations from any other sources" including the private sector.

3. Poor Infrastructure and General Environment for Scientists:

"Neither the funding, the infrastructure nor the general environment in India is attractive for top-level international scientists to leave the U.S. to work in India." This statement encapsulates the core problem.

Specific Pain Points: Delayed funding release, unpaid scholarships for research scholars (up to a year), and "whimsical ways in which science policies are changed with little discussion with scientists" are significant deterrents. The "Ramalingaswami re-entry fellowship" is cited as an example of abrupt policy changes.

Lack of National Policies for Senior Scientists: "Currently, there are no national policies to attract senior scientists from other countries."

4. Detrimental Social and Environmental Factors:

"The other detriment to attracting scientists (especially non-Indians) from abroad is India itself." Ramakrishnan points to a significant quality of life issue.

Decline in Public Spaces: "Today, the streets are filthy and full of trash, the sidewalks are not navigable, and the air is unbreathable in most cities... Which non-Indian would want that sort of life for themselves and their children?" This directly impacts the appeal of living and raising a family in India.

Singapore as a Counter-Example: Singapore's success in attracting talent is attributed to "high salaries with low taxes, and excellent scientific infrastructure," coupled with a "clean and well-run" society boasting "first-rate schools, health care, mass transit, and safety."

5. U.S. Science Landscape and Global Mobility Trends:

U.S. Funding Cuts: The U.S. is experiencing significant cuts in research programs and grants (e.g., $8 billion already cut from NIH, $18 billion projected; $5 billion cut from NSF; 25% cut to NASA budget).

Scientists Seeking Opportunities Abroad: "Many U.S. scientists are planning to move to other countries." Nature Careers shows a 32% increase in U.S. applications for European vacancies, and a Nature poll indicates 75% of respondents are "keen to leave the country."

Limited "Mass Exodus" to Europe: Despite increased interest, Ramakrishnan predicts "not a mass exodus" to Europe due to lower salaries, difficulties in moving, and the U.S. still being the "pre-eminent scientific country." He speaks from personal experience, having moved from the U.S. to England for half his U.S. salary.

6. Recommendations for India:

"India needs a strong, stable commitment to science, which means not only much more funding but also more stable funding, much better infrastructure and, just as importantly, insulating science from politics and excessive bureaucratic rules and regulations." This is the core scientific requirement.

Wednesday, June 18, 2025

 

Question 1: Which of the following findings from the recent rice study support Lamarck’s theory of acquired characteristics?

  1. Cold-tolerant rice traits were inherited without changes in DNA sequence.
  2. Hypomethylation near the ACT1 gene promoter was induced by cold exposure.
  3. The ability to tolerate cold persisted across five generations.
  4. Natural selection led to permanent mutations in the ACT1 gene.

Select the correct answer using the code below:

A. 1, 2 and 3 only
B. 1 and 4 only
C. 2 and 3 only
D. 1, 2, 3 and 4

 Answer: A. 1, 2 and 3 only

·         Statement 4 is incorrect: no permanent DNA mutations were responsible for cold tolerance.

Question 2: Which molecular mechanisms were reported in the cold-adapted rice study?

  1. Downregulation of MET1b DNA methyltransferase under cold stress
  2. Hypomethylation of ACT1 promoter leading to increased Dof1 binding
  3. Permanent coding sequence mutations in ACT1
  4. Multigenerational inheritance of an epiallele

Select the correct answer:

A. 1, 2 and 4 only
B. 2 and 3 only
C. 1 and 3 only
D. 3 and 4 only

Answer: A. 1, 2 and 4 only

·         Coding sequence mutations were not found; the adaptation emerged through epigenetic changes

 Question 3: Consider the following statements about the geographic distribution of ACT1 methylation in rice landraces:

  1. Southern China rice landraces predominantly have hypermethylated ACT1 promoters.
  2. Northern China landraces predominantly carry hypomethylated ACT1 promoters.
  3. ACT1 coding sequence varied significantly between these landraces.

Which of the statements are correct?

A. 1 only
B. 1 and 2 only
C. 2 and 3 only
D. 1, 2 and 3

Answer: B. 1 and 2 only

·         Statement 3 is incorrect because ACT1 coding sequences remained conserved; only methylation varied geographically.

Question 4 :Which of the following best illustrates transgenerational epigenetic inheritance observed in the rice study?

A. A plant gene mutates permanently under stress and passes to offspring
B. Cold exposure induces inheritable methylation changes without DNA mutation
C. Darwinian natural selection of random beneficial mutants
D. Single-generation physiological adaptation without hereditary transfer

Answer: B. Cold exposure induces inheritable methylation changes without DNA mutation

·         This aligns with the observed epigenetic inheritance of cold tolerance across generations.

Question 5: Which of the following terms best describes the heritable cold resistance seen in the rice study?

A. Somatic mutation
B. Horizontal gene transfer
C. Epigenetic inheritance
D. Gene flow

Answer: C. Epigenetic inheritance

·         Traits were passed down through methylation changes, not genetic code changes.

Question 6Which scientist’s work does the recent rice epigenetic study conceptually support?

A. Charles Darwin
B. August Weismann
C. Jean-Baptiste Lamarck
D. Gregor Mendel

Answer: C. Jean-Baptiste Lamarck

·         Because traits acquired during an organism's life were inherited by the offspring — echoing Lamarck's theory.

Question 7:Which of the following is true about gene ACT1 in the rice study?

  1. It is vital for plant growth and development.
  2. Its expression decreases in cold due to methylation in normal plants.
  3. In cold-adapted rice, the ACT1 gene was deleted.
  4. ACT1 expression continued in cold-adapted rice due to hypomethylation.

Select the correct code:

A. 1 and 2 only
B. 1, 2 and 4 only
C. 3 and 4 only
D. 2 and 3 only

Answer: B. 1, 2 and 4 only

·         ACT1 was not deleted in cold-adapted plants; it was still expressed due to reduced methylation.

Question 8: Which process allows gene expression to be altered without changing the underlying DNA sequence?
A. Mutation
B. Transcription
C. Translation
D. Epigenetic modification

Answer: D

 

Question 9: What was the key finding of the 2024 rice cold-tolerance study?
A. Mutation in ACT1 gene improved survival
B. Gene ACT1 was removed from genome
C. ACT1 stayed active due to absence of methylation
D. DNA sequence was changed by cold stress

Answer: C

 

Cold-Adaptive Rice & Epigenetics

 

Cold-Adaptive Rice & Epigenetics

The Study (Published in Cell, May 2024):

  • Plant Studied: Oryza sativa (rice)
  • Method: Exposed normal rice to low temperatures
  • Observation Tool: Quality and quantity of seeds produced
  • Result: Rice adapted to cold without genetic mutation but by altering epigenetic marks

Key Concepts:

  • ACT1 Gene:
    • Important for plant growth & development
    • Usually active in rice
    • Cold exposure adds methyl group (epigenetic tag) → turns it off
    • Cold-adapted rice avoids methylation → ACT1 stays active
  • Epigenetics:
    • Study of changes in gene expression without altering DNA sequence
    • Involves chemical tags like methyl groups on DNA
    • These changes can be heritable
  • Inheritance Observed:
    • Cold tolerance passed to 5 generations
    • Confirms environmental influence on heredity via epigenetic marks

Scientific Importance:

  • Supports Lamarck's theory (acquired traits can be inherited)
  • Challenges traditional view that only DNA mutations are inherited
  • No DNA mutation detected for cold tolerance → purely epigenetic change
  • Indicates environmental memory can be passed to next generations

Important Scientists & Terms:

  • Jean-Baptiste Lamarck (1809): Theory of Acquired Characters
  • Charles Darwin (1859): Theory of Natural Selection
  • August Weismann: Disproved Lamarck using mouse tail experiment
  • Gregor Mendel: Laws of Heredity using pea plants
  • Royal Alexander Brink (1956): Epigenetics clue from maize pigment
  • Arthur Riggs (1975): Proposed heritable epigenetic marks

UPSC Relevance:

  • Useful for GS Paper III – Science and Tech
  • Can be linked to:
    • Evolution & Genetics
    • Climate-resilient agriculture
    • Biotechnology & food security

 

🔑 Concept

📝 Key Point

Epigenetics

Gene expression changes without altering DNA sequence

Methylation

Addition of a methyl group that silences gene expression

ACT1 gene

Essential for plant growth; remains active in cold-adapted rice

Lamarckian Inheritance

Acquired traits passed to offspring (environment → trait → heritable)

Darwinian Evolution

Based on genetic variations and natural selection

Oryza sativa

Scientific name for rice plant

Royal Alexander Brink (1956)

Discovered epigenetic inheritance in maize pigmentation

Arthur Riggs (1975)

Proposed epigenetic marks can be inherited

Weismann barrier

Somatic changes can’t affect germline inheritance

Cold-adapted rice study (2024)

Proved epigenetic change inherited across 5 generations

 

 

 

Q: "Epigenetics is changing how we understand heredity and evolution." Discuss in light of recent research.

Introduction:

·         Define epigenetics — changes in gene activity without changes in DNA sequence.

·         Mention the recent rice cold-tolerance study as a breakthrough.

Body:

1.      The Study Highlights:

o    Oryza sativa exposed to cold → gene ACT1 stayed active due to absence of methylation.

o    Trait passed for 5 generations → suggests heritability of environmentally induced changes.

2.      Lamarck vs Darwin:

o    Lamarck: Traits acquired due to environment may be inherited.

o    Darwin: Only traits from genetic variation survive via natural selection.

o    Rice study gives partial validation to Lamarck, in epigenetic context.

3.      Scientific Milestones:

o    1956: Brink’s maize pigment mystery.

o    1975: Riggs' epigenetic inheritance proposal.

o    2024: First strong experimental proof of natural epigenetic inheritance.

4.      Implications:

o    Could reshape evolutionary biology, crop science, climate-resilient agriculture.

o    Environmental challenges can influence traits across generations, even without gene mutations.

Conclusion:

·         While DNA mutations remain central, epigenetics adds a layer of flexible, heritable change.

·         Evolution may not only be about "survival of the fittest" but also memory of survival.

 

What challenges do gig workers face?

 What challenges do gig workers face? Gig workers face several challenges, primarily revolving around the nature of temporary, project-based...