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Wednesday, June 25, 2025

Novo Nordisk Launches Wegovy in India for Obesity and Cardiovascular Health

The key information regarding Novo Nordisk's launch of Wegovy (semaglutide 2.4 mg) in India, focusing on its intended uses, benefits, and market context.

Main Themes:

1.     Dual Indication: Wegovy is positioned as a comprehensive solution addressing both chronic weight management and the reduction of major adverse cardiovascular events (MACE) in individuals with obesity.

2.     Clinical Efficacy: The drug demonstrates significant potential for substantial weight loss and a reduction in cardiovascular risks, supported by clinical study data.

3.     Addressing a Growing Health Crisis: The launch responds to the increasing prevalence of obesity in India and its associated health burdens.

4.     Market Competition and Access: Wegovy enters a market where another major player, Eli Lilly, has already launched a similar drug, Mounjaro, highlighting a growing focus on obesity and diabetes management in India.

Most Important Ideas/Facts:

  • Product Name and Manufacturer: Wegovy (semaglutide 2.4 mg) by Novo Nordisk.
  • Launch Date and Location: Launched in India on June 24, 2025.
  • Key Indications:Chronic weight management.
  • Reducing the risk of major adverse cardiovascular events (MACE) in individuals with obesity.
  • Mechanism of Administration: Once-weekly injectable therapy administered via a pen device.
  • Dosing Strengths: Available in five dose levels: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and a maintenance dose of 2.4 mg.
  • Notably, "The company has kept the price of the first three dose levels the same to help patients adjust their dosage without extra cost."
  • Clinical Efficacy Data:Weight Loss: "at least one in three people using Wegovy along with lifestyle changes may lose over 20% of their body weight."
  • Cardiovascular Risk Reduction: "It has also been proven to lower the risk of heart attacks, strokes and related deaths by 20% in people who already have heart disease and obesity."

Prevalence of Obesity in India:

"According to national health data, about 24% of Indian women and 23% of men live with obesity." This underscores the significant need for such treatments.

  • Expert Commentary: Vikrant Shrotriya, managing director of Novo Nordisk India, emphasizes that "Obesity is a long-term health condition that needs medical support."
  • Prescription Status: Wegovy is a "prescription-only medicine and should be used under medical supervision."
  • Competitive Landscape: Eli Lilly and Company launched its diabetes and obesity management drug Mounjaro (tirzepatide) in India in March, preceding Wegovy's launch.

In summary, Novo Nordisk's introduction of Wegovy in India represents a strategic move to address the multifaceted challenges of obesity and its cardiovascular complications, offering a clinically proven therapeutic option in a growing market.

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